allosteric inhibitor

allosteric inhibitor
аллостерический ингибитор
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аллостерический ингибитор

English-russian biological dictionary. 2013.

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  • Allosteric enzyme — Allosteric enzymes are enzymes that change their shape, or conformation, upon binding of a modulator. The word allosteric comes from the Greek allos, other and stereos , shape . An allosteric enzyme is an oligomer whose biological activity is… …   Wikipedia

  • Allosteric regulation — In biochemistry, allosteric regulation is the regulation of an enzyme or other protein by binding an effector molecule at the protein s allosteric site (that is, a site other than the protein s active site). Effectors that enhance the protein s… …   Wikipedia

  • Allosteric serotonin reuptake inhibitor — is a marketing classification invented by the pharmaceutical company Lundbeck for its selective serotonin reuptake inhibitor (SSRI) escitalopram, the S stereoisomer of the SSRI citalopram. It is based on the observation that the R isomer of… …   Wikipedia

  • allosteric inhibition — inhibition of an enzyme by binding of an inhibitor at an allosteric site that causes at the catalytic site either reduced binding affinity of the enzyme for the substrate or decreased rate of catalytic turnover …   Medical dictionary

  • allosteric effector — an enzyme inhibitor or activator that has its effect at a site other than the catalytic site of the enzyme; see also under site, and see allostery …   Medical dictionary

  • allosteric enzyme — An enzyme that has two structurally distinct forms, one of which is active and the other inactive. Active forms tend to catalyse the initial step in a pathway leading to the synthesis of molecules. The end product of this synthesis can act as a… …   Glossary of Biotechnology

  • Reuptake inhibitor — Escitalopram, a selective serotonin reuptake inhibitor (SSRI) used as an antidepressant. A reuptake inhibitor (RI), also known as a transporter blocker, is a drug that inhibits the plasmalemmal transporter mediated reuptake of a neurotransmitter… …   Wikipedia

  • Enzyme inhibitor — Enzyme inhibitors are molecules that bind to enzymes and decrease their activity. Since blocking an enzyme s activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. They are also used as herbicides and… …   Wikipedia

  • Negative allosteric modulator — A negative allosteric modulator (NAM) is a drug which decreases the activity of a receptor indirectly via disactivation of an allosteric site on the protein. NAMs are similar to inverse agonists in that they conteract overall receptor activation …   Wikipedia

  • Norepinephrine-dopamine reuptake inhibitor — Norepinephrine Dopamine …   Wikipedia

  • Serotonin–norepinephrine reuptake inhibitor — Serotonin No …   Wikipedia


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